FPS Pharmaceutical Sciences Exam 5 Practice 2025 – All-in-One Study Guide for Exam Success!

Drug absorption is significantly influenced by various factors, and the impact of physical activity on absorption is generally less pronounced compared to the other choices. While physical activity can influence the overall pharmacokinetics of a drug, such as by potentially altering blood flow and gastrointestinal motility, its effect is not as direct or substantial as the influences exerted by aspects like drug formulation, pH level, and competitive inhibition.

Drug formulation determines how the active ingredient is delivered and can affect the rate and extent of absorption. For example, a drug in a solid dosage form may be absorbed differently compared to one in a liquid formulation due to differences in disintegration and dissolution rates.

The pH level of the environment plays a critical role in drug absorption, particularly for weak acids and bases. The degree of ionization which varies with pH can significantly affect the solubility of the drug, thus influencing its ability to cross cell membranes.

Competitive inhibition occurs when other substances interfere with the absorption or metabolism of a drug, which can considerably reduce the availability of the drug. This can occur through various mechanisms including competition for transporters or metabolic enzymes.

In summary, while physical activity might have some effects on absorption, it is generally overshadowed by the more significant influences of drug formulation