How are hard capsule sizes sorted?

Hard capsule sizes are primarily sorted by volume size. This classification is based on the capsules' capacity to hold a specific volume of fill material, which is critical when determining the appropriate dosage for a medication. The size of the capsule directly affects the volume of active ingredients and excipients that can be encapsulated, making volume a crucial factor for developers when creating formulations for therapeutic use.

Capsules come in a variety of sizes, typically ranging from size 000 (largest) to size 5 (smallest), with each size corresponding to the volume it can contain. Accurate dosing is essential for efficacy and safety, and sorting capsules by volume size ensures that the intended dose can be reliably delivered.

While other factors such as weight, length, and shape might play a role in other aspects of capsule formulation or handling, they are not the primary criteria for sorting hard capsule sizes. Focusing on volume size allows for the most consistent and effective dosage delivery in pharmaceutical preparations.