What are the two sustained release polymers discussed in class?

The correct answer focuses on the sustained release characteristics of Ethylcellulose and Methacrylic acid copolymer, which are commonly employed in pharmaceutical formulations to control the release of active ingredients over an extended period.

Ethylcellulose is a polymer that serves as a matrix-forming agent in sustained release formulations. Due to its hydrophobic nature, it slows down the release of drugs by creating a barrier that the drug must diffuse through. This allows for prolonged drug action and maintains therapeutic levels in the bloodstream over an extended time frame.

Methacrylic acid copolymers, particularly in their various grades, are also widely used in the development of sustained release formulations. These polymers can be designed to respond to specific pH levels or ionic conditions, enabling a tailored release profile. This responsiveness makes them valuable in designing formulations for various delivery routes, including oral and transdermal systems.

The combination of these two polymers ensures that the drug is released at a controlled and predictable rate, leading to improved therapeutic outcomes and patient compliance.