What is the primary characteristic that distinguishes pellets from other dosage forms?

The primary characteristic that distinguishes pellets from other dosage forms is that they are composed of discrete smaller particles. This means that pellets consist of compact, spherical granules, typically ranging in size from 0.5 mm to 2 mm, which set them apart from larger unit dosage forms such as tablets or capsules. Each pellet functions as a mini dosage form, allowing for a range of release profiles, including sustained or modified release, depending on their composition and processing. The discrete nature of these particles enables better flow properties and uniformity in blending with other ingredients, which is crucial in the formulation of pharmaceutical products.

The other characteristics mentioned, such as a monolithic structure, a single unit dose, or high water solubility, do not accurately represent the fundamental nature of pellets. Unlike monolithic structures that are typically solid and homogeneous, pellets maintain their discrete physical identity. Additionally, while pellets may be used in a variety of dosage forms, they can be administered in multiple pellets per dose rather than strictly as a single unit dose. Furthermore, water solubility varies among pellets based on their composition, but it does not define their primary characteristic as a dosage form. Thus, the identification of pellets as discrete smaller particles is a critical factor that distinguishes them in