What type of polymers are used for taste masking in pharmaceutical formulations?

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Cationic polymers are effective for taste masking in pharmaceutical formulations due to their ability to interact with the negatively charged taste receptors on the tongue. This interaction can reduce the perception of bitter taste by forming a protective layer around the drug particles, thereby preventing their release and interaction with taste receptors.

Cationic polymers can also enhance the stability and solubility of poorly water-soluble drugs, further contributing to their application in taste-masking formulations. Unlike other types of polymers, cationic polymers possess properties that can specifically target taste modulation, making them particularly useful in oral dosage forms aimed at improving patient compliance, especially in pediatric and geriatric populations where taste is a significant factor in medication adherence.

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