Which defect occurs when the top of a tablet is cut off during production?

Capping is the phenomenon that occurs when the top of a tablet is cut off or separates from the rest of the tablet during production. This defect typically arises due to insufficient binding forces within the tablet, which can result from issues such as incorrect tableting pressures, poor formulation, or the presence of too much air trapped in the tablet during compression. Capping can lead to a decrease in tablet integrity and uniformity, and it often affects the tablet’s appearance and performance.

The emphasis in addressing capping is on maintaining appropriate compression techniques and ensuring that the tablet formulation is well-optimized to minimize air entrapment and enhance bonding among the tablet components. When production parameters are adjusted correctly, the risk of capping can be significantly reduced, ensuring a better quality product.

Understanding this defect is crucial as it provides insight into the manufacturing process and highlights the importance of proper technique and formulation in tablet production. Other defects like whiskering, mottling, and laminating pertain to different issues in tablet production, each requiring specific strategies for mitigation which are distinct from those needed to address capping.