Which problem in the manufacturing of tablets is linked to an unequal distribution of components?

Mottling is specifically associated with an uneven distribution of components within a tablet formulation. This issue arises when active pharmaceutical ingredients (APIs) or colorants are not uniformly mixed with the excipients in the tablet. As a result, some areas of the tablet may appear darker or lighter than others, leading to an undesirable, mottled effect on the tablet's appearance.

The other options do not relate directly to the distribution of components in the same way. Picking or sticking often relates to tablet adhesion issues during the manufacturing process, while capping usually involves the separation of the tablet top from the main body, which is more about pressure and moisture issues. Whiskering refers to the formation of fine filament-like protrusions on the tablet surface, typically related to factors such as moisture or formulation characteristics rather than component distribution.