Which tableting defect is caused by the tablet being broken into thin layers?

Laminating is the defect characterized by the separation of a tablet into thin layers. This phenomenon occurs primarily due to insufficient binding between the tablet components during the compression process. Factors contributing to laminating include inadequate compression force, high moisture content, or low tabletability of the excipients. As a result, when the tablet is subjected to even slight stress, it fails to hold its integrity and splits into distinct layers, rather than maintaining a solid, unified structure.

Understanding this defect is crucial in tablet formulation and manufacturing, as addressing the causes of laminating can help improve the overall quality and performance of the final product. Optimizing the formulation, selecting the right excipients, and ensuring proper compression techniques can mitigate the risk of laminating in tablet production.